Work in progressRenamed from /mrna on 2026-05-21 — the module is structurally a CAR cassette assembler, not pure mRNA design. Paste a real binder sequence for now; candidate-library handoff and full mRNA-LNP optimization are still on the roadmap.

CAR Design

Assemble a CAR construct cassette from a binder (VHH or scFv) plus hinge / TM / costim / CD3ζ domains. Output will be the codon-optimized mRNA cassette ready for LNP delivery once the backend path is wired.

Binder Input
Provide the binder protein sequence to assemble into a CAR cassette

Candidate picker is intentionally hidden until it can read real FASTA from the candidate library.

CAR Construct Architecture
5' UTR — Signal peptide — VHH — Hinge — TM — Costim — CD3ζ — 3' UTR — polyA
VHH120 aa
Hinge45 aa
TM21 aa
Costim42 aa
CD3z112 aa
VHH (120 aa)Hinge (45 aa)TM (21 aa)Costim (42 aa)CD3z (112 aa)
Design Options