DesignPipeline

Pipeline

Configure and launch an end-to-end antibody design workflow

Target Antigen

Comma-separated chain:residue pairs defining the target epitope

Design Tool

Parameters

CAR Options

CAR Scoring

Evaluate CAR-T construct compatibility

mRNA Optimization

Optimize codon usage for mRNA delivery

Exosome Assessment

Assess exosome surface display potential

Pipeline Stages

1

epitope

2

backbone

3

sequence

4

validation

5

scoring

6

optimization

Configure parameters and launch to begin

Stage Details

EpitopeAnalyze target surface and identify binding hotspots
BackboneGenerate de novo protein backbones via diffusion models
SequenceDesign amino acid sequences using inverse folding
ValidationPredict structures and verify binding with AlphaFold
ScoringMulti-property scoring: binding, stability, humanness, developability
OptimizationRefine top candidates for expression and delivery