OpenDDE Interface

Beta

Preview antibody–antigen co-folding with the OpenDDE ABAG checkpoint on internal GPU compute.

OpenDDE is a preview backend. Compare important candidates with Boltz-2 or AlphaFold 3 and validate experimentally before making decisions.

Name (optional — used in job list instead of random ID)

Antibody — VHH / scFv (single block) or Fab (VH + VL, blank line between)

Antigen input

1Upload antigen structure

Upload antigen PDBRecommendedDrop an antigen structure or browse · .pdb / .ent · max 20 MiBBrowse

Selected antigen chains are retained as a forced structural template, preserving multimeric assembly while the antibody–antigen complex is predicted.

Complete antigen sequence(s)Optional

Use this when the structure has unresolved residues. The complete sequence is aligned to each selected PDB chain before submission; incompatible mappings are rejected rather than guessed.

Contact cutoff (Å)

Structure model

Backend

OpenDDE Preview — runs the antibody–antigen checkpoint on internal GPU and falls back to Boltz-2 if unavailable.

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