G-protein Design-around
M1Upload candidate viral glycoproteins, run VSV-G / Cocal-G 354 technical triage, and download a review-ready CSV / JSON evidence pack.
Green / amber / red are technical triage bands only. The output supports wet-lab and IP review; it is not an FTO opinion.
Submit an assessment to see status, top candidate, and downloads here.
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Global amino-acid identity to the VSV-G reference. <70% is the useful design-around watch line; <85% alone is not enough.
Global identity to Cocal-G. A candidate close to Cocal-G can recreate the same 354-equivalent risk story.
Candidate residues aligned to VSV-G positions 47 and 354. This is a triage mapping, not a claim chart.
Technical triage band: green, amber, red, or unknown. It is evidence for review, not a legal conclusion.
1. Prepare candidates
Upload a curated candidate FASTA or use a narrow UniProt query. Avoid broad polyprotein dumps for the first screen.
2. Add references
Optional VSV-G / Cocal-G FASTA references make the run reproducible. If omitted, the backend fetches P03522 and O56677.
3. Run and poll
The API stores inputs and outputs under a job ID, then the page polls until the assessment finishes.
4. Download review pack
Download CSV for spreadsheet review, JSON for downstream scripts, and manifest for provenance.
assessments.csv
Spreadsheet review table.
assessments.json
Machine-readable full result.
manifest.json
Inputs, references, counts, risk note.